BS-112
(IMD of Xarelto® , Oral)

BS-112 is an anticoagulant agent, a factor Xa inhibitor, indicated for the treatment of deep vein thrombosis, pulmonary embolism, etc. It is an incrementally modified drug (IMD) of Xarelto® (15 mg or 20 mg ; Need to be taken with food). BS-112 is being developed to decrease the food effect to improve patient convenience and compliance.
Active Pharmaceutical Ingredient : Rivaroxaban
Indication : Deep vein thrombosis, Pulmonary embolism
Global Xarelto® Sales : € 3,631 million in 2018
Development Objective : Decrease of food effect to improve patient convenience
R&D status : Confirmation of the reduced food effect through a PK test in beagle dogs
  • Reduced food effect